The impact of US Most Favoured Nation pricing on European markets is already happening now.
Watch this expert insight and find out what it means for your launch strategies, pricing decisions, and payer relationships.
35% Drop in EU drug launches after the first MFN policy was introduced | -60% Fewer early access applications in France (25 in 2024 vs. 10 last year) | >90% Of drugs approved in 2025 that launched first in the US are still not available elsewhere |
What manufacturers are doing right now
In a recent CELforPharma webinar, Megan O'Brien of Access Infinity explained the strategic shifts already under way. These are not theoretical scenarios. They are live decisions affecting patient access across Europe today.
"The objective from pharma for these strategies is quite straightforward. It is all about maintaining access while minimising transparent list price erosion."
Megan O'Brien, Associate Director, Access Infinity · CELforPharma webinar, May 2026
| 🌍 | Selective and delayed launches in European markets | 🚫 | Product withdrawals from specific countries |
| 📈 | Tighter international pricing corridors and higher UK launch prices | 🤝 | Growth in managed entry agreements and outcomes-based contracts |
| 💳 | Greater consideration of out-of-pocket payment models in Europe | 🏭 | Shifts in manufacturing strategy to reduce tariff exposure |
For payers, this creates new pressures too. Managed entry agreements are preferred by payers but carry a high administrative burden. As more manufacturers move in this direction, payers will increasingly need to adopt these models to secure continuous access to medicines in their markets.
Continue your learning about Market Access and Payers
If you’d like to learn more on this topic, CELforPharma also offers two 1-day, hands-on courses that will get you up the learning curve quickly!
Understanding Pharma Market Access in the US
With Dr Nick Proctor & Louisa Oliver Byrne
Understanding Pharma Market Access & Payers in Europe
With Dr Nick Proctor & Megan O'Brien
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